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<t> ROTEM/TEG </t> assay nomenclature, activation agents, and assay information
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 ROTEM/TEG  assay nomenclature, activation agents, and assay information

Journal: Clinical and Experimental Emergency Medicine

Article Title: Update on the pathophysiology and management of acute trauma hemorrhage and trauma-induced coagulopathy based upon viscoelastic testing

doi: 10.15441/ceem.24.202

Figure Lengend Snippet: ROTEM/TEG assay nomenclature, activation agents, and assay information

Article Snippet: EXTEM (ROTEM) , Tissue factor , Extrinsic coagulation factors (VII).

Techniques: Activation Assay, Coagulation, Polymerization Assay, FIBTEM Assay, Biomarker Discovery, Functional Assay, Lysis, Activity Assay

Example of a stepwise, evidence-based clinical treatment alogorithm for early rotational thromboelastometry (ROTEM; Werfen)-guided hemostatic management (test result after 5 minutes of ROTEM operation, A5) in bleeding trauma patients including a recommendation for FIBTEM-guided fibrinogen substitution through the administration of cryoprecipitate using a dose calculator. The ROTEM triggers for the given interventions are based upon consensus from a multidisciplinary conference held in the United States in 2014 . TIC, trauma-induced coagulopathy; ABG, arterial blood gas analysis; TXA, tranexamic acid; EXTEM, extrinsic thromboelastometry; INTEM, intrinsic thromboelas­tometry; FIBTEM, fibrinogen thromboelastometry (platelet-inhibited thromboelastometry); APTEM, aprotinine thromboelastometry (antifibrinolytic thromboelastometry); EX, ROTEM EXTEM assay; FIB, ROTEM FIBTEM assay; ML, maximum lysis; MCF, maximum clot firmness; BW, body weight; CT, clotting time; FFP, fresh frozen plasma.

Journal: Clinical and Experimental Emergency Medicine

Article Title: Update on the pathophysiology and management of acute trauma hemorrhage and trauma-induced coagulopathy based upon viscoelastic testing

doi: 10.15441/ceem.24.202

Figure Lengend Snippet: Example of a stepwise, evidence-based clinical treatment alogorithm for early rotational thromboelastometry (ROTEM; Werfen)-guided hemostatic management (test result after 5 minutes of ROTEM operation, A5) in bleeding trauma patients including a recommendation for FIBTEM-guided fibrinogen substitution through the administration of cryoprecipitate using a dose calculator. The ROTEM triggers for the given interventions are based upon consensus from a multidisciplinary conference held in the United States in 2014 . TIC, trauma-induced coagulopathy; ABG, arterial blood gas analysis; TXA, tranexamic acid; EXTEM, extrinsic thromboelastometry; INTEM, intrinsic thromboelas­tometry; FIBTEM, fibrinogen thromboelastometry (platelet-inhibited thromboelastometry); APTEM, aprotinine thromboelastometry (antifibrinolytic thromboelastometry); EX, ROTEM EXTEM assay; FIB, ROTEM FIBTEM assay; ML, maximum lysis; MCF, maximum clot firmness; BW, body weight; CT, clotting time; FFP, fresh frozen plasma.

Article Snippet: EXTEM (ROTEM) , Tissue factor , Extrinsic coagulation factors (VII).

Techniques: FIBTEM Assay, Lysis, Coagulation, Clinical Proteomics