Journal: Clinical and Experimental Emergency Medicine
Article Title: Update on the pathophysiology and management of acute trauma hemorrhage and trauma-induced coagulopathy based upon viscoelastic testing
doi: 10.15441/ceem.24.202
Figure Lengend Snippet: Example of a stepwise, evidence-based clinical treatment alogorithm for early rotational thromboelastometry (ROTEM; Werfen)-guided hemostatic management (test result after 5 minutes of ROTEM operation, A5) in bleeding trauma patients including a recommendation for FIBTEM-guided fibrinogen substitution through the administration of cryoprecipitate using a dose calculator. The ROTEM triggers for the given interventions are based upon consensus from a multidisciplinary conference held in the United States in 2014 . TIC, trauma-induced coagulopathy; ABG, arterial blood gas analysis; TXA, tranexamic acid; EXTEM, extrinsic thromboelastometry; INTEM, intrinsic thromboelastometry; FIBTEM, fibrinogen thromboelastometry (platelet-inhibited thromboelastometry); APTEM, aprotinine thromboelastometry (antifibrinolytic thromboelastometry); EX, ROTEM EXTEM assay; FIB, ROTEM FIBTEM assay; ML, maximum lysis; MCF, maximum clot firmness; BW, body weight; CT, clotting time; FFP, fresh frozen plasma.
Article Snippet: EXTEM (ROTEM) , Tissue factor , Extrinsic coagulation factors (VII).
Techniques: FIBTEM Assay, Lysis, Coagulation, Clinical Proteomics